PIBALE (Plateforme d’Irradiation de Biomolécules et d’Agrégats Libres ou Environnés)
A new experimental set-up, dedicated to the study of large molecules (peptides), mass-selected biomolecular clusters or nanosolvated biomolecules, is currently in its final stage of development.
In this experimental set-up, the molecular ion beam is formed by an electrospray ionization source, collimated in an ion funnel before being mass-selected by a quadrupole mass filter. In order to increase the beam density before entering the collision zone, the selected ions are then accumulated and bunched in a 3D Paul trap using buffer gas cooling. This target beam then crosses a keV atomic ion beam produced by an ECR ion-source. The projectile ion beam is shaped by a quadrupole triplet to maximize the beam overlap. Charged fragments created by the collision are then analyzed by a vertical time-of-flight mass spectrometer and collected on a position-sensitive detector allowing kinematic analysis of the main ion-induced fragmentation channels.
Contact : Alain Méry, Jean-Christophe Poully, Jimmy Rangama, Violaine Vizcaino
PhD : Mathieu Lalande, Marwa Abdelmouleh
Recent publications
Recent PhD
Lucas Schwob, Ionisation et fragmentation de biomolécules sélectionnées en masse induites par impact d’ions et photo-absorption, université Caen Normandie, 2016, https://tel.archives-ouvertes.fr/tel-01465838/document